Airways oedema
Summary
This test is for a gene mutation that contributes to breathing difficulties by causing swelling (oedema) in the airways. It is most commonly found in English bulldogs, French bulldogs and Norwich terriers, and has been also been found more rarely in Staffies, German Spitz and Pomeranians.
Respiratory problems are common in a number of dog breeds. It is especially common for short-nosed breeds to have trouble breathing. Swelling of the airways makes this problem worse.
The airways of dogs with two copies of this gene mutation are on average significantly impacted compared to dogs with one copy or no copies of this mutation. We classify this test as a marker test because the effect can vary widely between individual dogs.
Gene or region and technical reference
Gene: ADAMTS3 (marker). Reference: Marchant et al, 2019
Reported alleles
n. Test developed using artificial DNA, animal controls.
AO. Test developed using artificial DNA.
Panels: groups of tests that are often ordered together
This test is not in any panels.
