We are taking an Easter break between the Easter and ANZAC day long weekends. You can still place orders now, and also while we are on break. If we we receive but don't finish testing your samples before Easter they will be at the top of our list when we re-open.
Juvenile hereditary cataract (JHC)
Summary
Cataract is an eye disease characterised by clouding of the eyes' lens, leading to impaired vision and then blindness. This form of inherited cataract (juvenile hereditary cataract or JHC) is found in both eyes simultaneously and usually causes complete blindness by 2-3 years of age. It is most commonly found in Boston terriers, Staffies and French Bulldogs.
Cataract treatment requires eye surgery.
JHC requires two copies of a variant of the HSF4 gene, one from each parent, to develop in dogs. It can both males and females equally. Carriers (dogs with a JHC n genotype) won't have JHC but can pass the gene on to offspring.
Gene or region and technical reference
Gene: HSF4 (causative). Reference: Mellersh et al. (2006)
Reported alleles
n. Test developed using artificial DNA, animal controls.
JHC. Test developed using artificial DNA.
Panels: groups of tests that are often ordered together
This test is not in any panels.
