Episodic falling syndrome (CKCS) (EF)
Summary
Episodic falling syndrome (EFS) affects some Cavalier King Charles Spaniels, starting between 3 and 7 months. The main sign is stiff or locked muscles that may cause a dog to jerk, hop like a bunny, or walk stiffly with what is sometimes called a 'deer stalker' gait. These episodes are usually brief, lasting less than 5 minutes, and go away on their own. However, the length of time they last can vary. Episodes may be triggered by exercise, excitement or stress.
Testing for a mutant form of the BCAN gene which causes EFS, can inform breeding choices. Testing can also help confirm or correct diagnoses, as the condition has similar symptoms to other disorders and could be misdiagnosed.EFS requires two copies of the mutant BCAN gene, one from each parent, to develop in dogs. It affects both males and females equally. Carriers (one copy) won't have EFS, but can pass the gene on to offspring.
Gene or region and technical reference
Gene: BCAN (causative). Reference: Forman et al. (2012)
Reported alleles
n. Test developed using artificial DNA, animal controls.
EFS. Test developed using artificial DNA, animal carriers.
Panels: groups of tests that are often ordered together
This test is in the CKCS health mini-panel.
