Episodic falling syndrome (CKCS) (EF)

Summary

Episodic falling syndrome (EFS) affects some Cavalier King Charles Spaniels, starting between 3 and 7 months. The main sign is stiff or locked muscles that may cause a dog to jerk, hop like a bunny, or walk stiffly with what is sometimes called a “deer stalker” gait. These episodes are usually brief, lasting less than 5 minutes, and go away on their own. However, the length of time they last can vary. Episodes may be triggered by exercise, excitement or stress.

Testing for a mutant form of the BCAN gene which causes EFS, can inform breeding choices. Testing can also help confirm or correct diagnoses, as the condition has similar symptoms to other disorders and could be misdiagnosed.

EFS requires two copies of the mutant BCAN gene, one from each parent, to develop in dogs. It affects both males and females equally. Carriers (one copy) won’t have EFS, but can pass the gene on to offspring.

Gene or region and technical reference

Gene: BCAN (causative). Reference: Forman et al. (2012)

Reported alleles

n. Test developed using artificial DNA, animal controls.

EFS. Test developed using artificial DNA, animal carriers.

Panels: groups of tests that are often ordered together

This test is not in any panels.

Order tests

There is a one-off sample processing fee of $40 per animal plus the cost of your tests.

How many animals are you testing? Discount or society code:


Panels


Colour panels

$24 B locus ... more

$35 Coat type ... more

$16 D locus ... more

$16 E locus ... more


Working dogs

$59 Australian Kelpie panel ... more

$26 Working dog CA ... more

$54 Working dog core panel ... more


Good looks


Coat characteristics

$9 Coat length L (common form) (L) ... more

$9 Coat length L2 (L2) ... more

$9 Curly coat ... more

$9 Improper coat ... more

$14 Shedding ... more


Coat colour

$9 B locus brown (bc allele) (bc) ... more

$9 B locus brown (bd allele) (bd) ... more

$9 B locus brown (bs allele) (bs) ... more

$9 D locus dilute d (common type) (d) ... more

$9 D locus dilute d2 (Chow Chow type) (d2) ... more

$9 E locus melanistic mask ... more

$9 E locus red/black ... more

$9 K locus dominant black ... more


Good health


Australian Kelpies

$14 Intestinal lipid malabsorption (ILM) ... more


Good health


CKCS

$14 Episodic falling syndrome (CKCS) (EF)

$14 Medium-chain acyl co-A dehydrogenase deficiency (CKCS) (MCADD) ... more


Multiple breeds

$14 Airways oedema ... more

$14 Degenerative myelopathy (DM) ... more

$14 Hyperuricosuria (HUU) ... more

$14 Ivermectin and multidrug sensitivity ... more

$14 Myxomatous mitral valve disease (MMVD) ... more

$14 Progressive retinal atrophy - PRCD (PRA-PRCD) ... more

$14 Progressive retinal atrophy CORD1 (PRA-cord1) ... more

$14 Screw tail ... more


Pure- and part-bred Labradors

$14 Labrador centronuclear myopathy (CNM) ... more

$14 Labrador exercise induced collapse (EIC) ... more

$14 Labrador hereditary nasal parakeratosis (HNPK) ... more


Pure- and part-bred NSDTR

$14 Cleft lip/palate and syndactyly (CLPS) ... more

$14 Cleft palate (CP1) ... more


Working dogs

$14 Cerebellar abiotrophy marker (LINGO3) (CA LINGO3) ... more

$14 Cerebellar abiotrophy marker (VMP1) (CA VMP1) ... more

$14 Collie eye anomaly (CEA) ... more

$14 Trapped neutrophil syndrome (TNS) ... more

Tests can be in the list more than once when the gene in question has more than one effect. It is OK to select the same test once or more than once, the price is the same.