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Cerebellar abiotrophy marker (LINGO3) (CA: LINGO3)

Summary

Cerebellar abiotrophy (CA) has been reported in working Kelpies. Dogs affected by CA can show head or neck tremors, problems with their balance, exaggerated or erratic leg movement and problems eating or drinking from a bowl.

This test (CA: LINGO3) is associated with a form of CA that usually becomes evident in pups between 8 and 12 weeks of age.

A positive result for this test (T T) does not guarantee that your pup will develop early-onset CA, but it is a strong guide. In the original study, 16 of 19 affected pups had a T T result for this marker, while only 19 of 146 healthy dogs showed the same T T result.

The other possible results for this test are T C or C C. Dogs with a T C result do not have a high risk of CA but can potentially produce T T pups.

This form of CA has been found in border collies as well as Kelpies.

More info...

Gene or region and technical reference

Gene: LINGO3 (marker). Reference: Pan. (2017) Thesis

Reported alleles

C. Test developed using manufactured DNA, animal controls.

T. Test developed using manufactured DNA, animal cases.

Panels: groups of tests that are often ordered together

This test is in the Australian Kelpie panel.

This test is in the working dog CA panel.

This test is in the working dog core panel.


dog

CA can become obvious in pups as young as 8 weeks old.

Order tests

There is a one-off sample processing fee of $40 per animal plus the cost of your tests.

How many animals are you testing? Discount or society code:


Panels


Colour panels

$24 B locus ... more

$16 E locus ... more


Working dogs

$59 Australian Kelpie panel ... more

$26 Working dog CA (CA panel) ... more

$54 Working dog core panel ... more


Good looks


Coat characteristics

$9 Coat length L (common form) (L) ... more

$9 Coat length L2 (L2) ... more

$9 Curly coat ... more

$9 Improper coat ... more


Good health


Australian Kelpies

$14 Intestinal lipid malabsorption (ILM) ... more


Good looks


Coat colour

$9 B locus brown (bc allele) (bc) ... more

$9 B locus brown (bd allele) (bd) ... more

$9 B locus brown (bs allele) (bs) ... more

$9 D locus dilute d2 (Chow Chow type) (d2) ... more

$9 E locus melanistic mask ... more

$9 E locus red/black ... more


Good health


Multiple breeds

$14 Degenerative myelopathy (DM) ... more

$14 Progressive retinal atrophy - PRCD (PRA-PRCD) ... more


Working dogs

$14 Cerebellar abiotrophy marker (LINGO3) (CA: LINGO3)

$14 Cerebellar abiotrophy marker (VMP1) (CA: VMP1) ... more

$14 Collie eye anomaly (CEA) ... more

$14 Trapped neutrophil syndrome (TNS) ... more

Tests can be in the list more than once when the gene in question has more than one effect. It is OK to select the same test once or more than once, the price is the same.