Progressive retinal atrophy - PRCD (PRA-PRCD)

Summary

PRA-PRCD causes late-onset blindness in dogs. Dogs with PRA-PRCD go night-blind first as the rod cells in their retina are lost. They go completely blind when the cone cells in the retina also die.

Breeds known to be affected by PRA-PRCD include Miniature and Toy poodles, Australian cattle dogs (including stumpy-tailed cattle dogs), Silky terriers, Labrador retrievers and Nova Scotia Duck Tolling Retrievers.

Cavoodles and other poodle crosses that are not first-generation crosses are also at risk of PRA-PRCD.

PRA-PRCD is an autosomal recessive disorder. Autosomal disorders are equally likely to affect male or female dogs, while "recessive" means that a dog needs to inherit the PRA-PRCD mutation from both its parents to be affected.

Gene or region and technical reference

Gene: PRCD (causative). Reference: Zangerl et al. (2006)

Reported alleles

n. Test developed using manufactured DNA, animal controls.

PRCD. Test developed using manufactured DNA, animal cases.

Panels: groups of tests that are often ordered together

This test is not in any panels.


dog

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There is a one-off sample processing fee of $40 per animal plus the cost of your tests.

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$24 B locus ... more

$35 Coat type ... more

$16 D locus ... more

$16 E locus ... more


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$14 Shedding ... more


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$9 B locus brown (bd allele) (bd) ... more

$9 B locus brown (bs allele) (bs) ... more

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Good health


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$14 Intestinal lipid malabsorption (ILM) ... more


Good health


Multiple breeds

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$14 Degenerative myelopathy (DM) ... more

$14 Hyperuricosuria (HUU) ... more

$14 Ivermectin and multidrug sensitivity ... more

$14 Myxomatous mitral valve disease (MMVD) ... more

$14 Progressive retinal atrophy - PRCD (PRA-PRCD)

$14 Progressive retinal atrophy CORD1 (PRA-cord1) ... more


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$14 Myxomatous mitral valve disease (MMVD) ... more


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Working dogs

$14 Cerebellar abiotrophy marker (LINGO3) (CA LINGO3) ... more

$14 Cerebellar abiotrophy marker (VMP1) (CA VMP1) ... more

$14 Collie eye anomaly (CEA) ... more

$14 Trapped neutrophil syndrome (TNS) ... more

Tests can be in the list more than once when the gene in question has more than one effect. It is OK to select the same test once or more than once, the price is the same.