Labrador exercise induced collapse (EIC)

Summary

Exercise induced collapse (EIC) is exactly what it sounds like. Dogs affected by EIC will collapse or start to stagger during intense exercise, with their back legs starting to go wobbly first. Collapsed dogs don't lose consciousness and will usually recover by themselves as long as they are made to rest rather than go back to work. Treatment simply consists of preventing the dog from doing strenuous exercise.

EIC is most common in Labrador retrievers, and genetic testing is recommended for both pure-bred and part-bred Labradors. It has also been found in Chesapeake Bay and Curly-coated retrievers, Pembroke Welsh corgis and Boykin spaniels. EIC is not known to occur in pure-bred Golden Retrievers, NSDTRs or Flat-coated retrievers.

EIC is an autosomal recessive disorder. Autosomal disorders are equally likely to affect male or female dogs, while "recessive" means that a dog needs to inherit the EIC mutation from both parents to be affected.

Gene or region and technical reference

Gene: DNM1 (marker). Reference: Patterson et al. (2008)

Reported alleles

n. Test developed using artificial DNA and animal controls.

EIC. Test developed using artificial DNA.

Panels: groups of tests that are often ordered together

This test is not in any panels.

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There is a one-off sample processing fee of $40 per animal plus the cost of your tests.

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Panels


Colour panels

$24 B locus ... more

$35 Coat type ... more

$16 D locus ... more

$16 E locus ... more


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$14 Shedding ... more


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$9 B locus brown (bd allele) (bd) ... more

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$9 D locus dilute d2 (Chow Chow type) (d2) ... more

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Good health


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$14 Intestinal lipid malabsorption (ILM) ... more


Good health


Multiple breeds

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$14 Degenerative myelopathy (DM) ... more

$14 Hyperuricosuria (HUU) ... more

$14 Ivermectin and multidrug sensitivity ... more

$14 Myxomatous mitral valve disease (MMVD) ... more

$14 Progressive retinal atrophy - PRCD (PRA-PRCD) ... more

$14 Progressive retinal atrophy CORD1 (PRA-cord1) ... more


Pure- and part-bred CKCS

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$14 Episodic falling syndrome (CKCS) (EF) ... more

$14 Medium-chain acyl co-A dehydrogenase deficiency (CKCS) (MCADD) ... more

$14 Myxomatous mitral valve disease (MMVD) ... more


Pure- and part-bred Labradors

$14 Labrador centronuclear myopathy (CNM) ... more

$14 Labrador exercise induced collapse (EIC)

$14 Labrador hereditary nasal parakeratosis (HNPK) ... more


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Working dogs

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$14 Collie eye anomaly (CEA) ... more

$14 Trapped neutrophil syndrome (TNS) ... more

Tests can be in the list more than once when the gene in question has more than one effect. It is OK to select the same test once or more than once, the price is the same.