DNA testing for health and appearance genes in dogs
Learn about one of the tests we do: Cerebellar abiotrophy marker (LINGO3)
Cerebellar abiotrophy (CA) has been reported in working Kelpies. Dogs affected by CA can show head or neck tremors, problems with their balance, exaggerated or erratic leg movement and problems eating or drinking from a bowl.
This test (CA: LINGO3) is associated with a form of CA that usually becomes evident in pups between 8 and 12 weeks of age.
A positive result for this test (T T) does not guarantee that your pup will develop early-onset CA, but it is a strong guide. In the original study, 16 of 19 affected pups had a T T result for this marker, while only 19 of 146 healthy dogs showed the same T T result.
The other possible results for this test are T C or C C. Dogs with a T C result do not have a high risk of CA but can potentially produce T T pups.
This form of CA has been found in border collies as well as Kelpies.
Gene or region and technical reference
Gene: LINGO3 (marker). Reference: Pan. (2017) Thesis, Wade et al. (2022)
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