Cerebellar abiotrophy marker (VMP1) (CA VMP1)

Summary

Cerebellar abiotrophy (CA) has been reported in working Kelpies. Dogs affected by CA can show head or neck tremors, problems with their balance, exaggerated or erratic leg movement and problems eating or drinking from a bowl.

This test (CA: VMP1) is associated with a form of CA that first appears in young dogs rather than pups.

A positive result for this test (A A) is a strong guide that your dog has or will develop CA. In the original study, 8 of 13 dogs with later-onset CA had an A A result for this marker, while none of the healthy dogs showed the same A A result.

Other possible results for this test are A C or C C. Dogs with an A C result do not have a high risk of CA but can potentially produce A A pups.

This form of CA has been found in border collies as well as Kelpies.

More info...

Gene or region and technical reference

Gene: VMP1 (marker). Reference: Pan. (2017) Thesis, Wade et al. (2022)

Reported alleles

C. Test developed using manufactured DNA, animal controls.

A. Test developed using manufactured DNA, animal cases.

Panels: groups of tests that are often ordered together

This test is in the Australian Kelpie panel.

This test is in the working dog CA panel.

This test is in the working dog core panel.


dog

This form of CA has been diagnosed in dogs between 4 and 16 months old.

Order tests

There is a one-off sample processing fee of $40 per animal plus the cost of your tests.

How many animals are you testing? Discount or society code:


Panels


Colour panels

$24 B locus ... more

$35 Coat type ... more

$16 D locus ... more

$16 E locus ... more


Panels by breed

$80 CKCS health mini-panel ... more


Working dogs

$59 Australian Kelpie panel ... more

$26 Working dog CA ... more

$54 Working dog core panel ... more


Good looks


Coat characteristics

$9 Coat length L (common form) (L) ... more

$9 Coat length L2 (L2) ... more

$9 Curly coat ... more

$9 Curly coat type 2 ... more

$9 Improper coat ... more

$14 Shedding ... more


Coat colour

$9 B locus brown (bc allele) (bc) ... more

$9 B locus brown (bd allele) (bd) ... more

$9 B locus brown (bs allele) (bs) ... more

$9 D locus dilute d (common type) (d) ... more

$9 D locus dilute d2 (Chow Chow type) (d2) ... more

$9 E locus melanistic mask ... more

$9 E locus red/black ... more

$9 I locus intensity dilution ... more

$9 K locus dominant black ... more


Good health


Australian Kelpies

$14 Intestinal lipid malabsorption (ILM) ... more


Good health


Multiple breeds

$14 Airways oedema ... more

$14 Congenital multifocal retinopathy 1 (Mastiff type) (CMR1) ... more

$14 Degenerative myelopathy (DM) ... more

$14 Hyperuricosuria (HUU) ... more

$14 Ivermectin and multidrug sensitivity ... more

$14 Myxomatous mitral valve disease (MMVD) ... more

$14 Progressive retinal atrophy - PRCD (PRA-PRCD) ... more

$14 Progressive retinal atrophy CORD1 (PRA-cord1) ... more


Pure- and part-bred CKCS

$14 Congenital macrothrombocytopenia (CKCS type) (CM) ... more

$14 Curly coat/dry eye syndrome (CKCS) (CKCSID) ... more

$14 Episodic falling syndrome (CKCS) (EF) ... more

$14 Medium-chain acyl co-A dehydrogenase deficiency (CKCS) (MCADD) ... more

$14 Myxomatous mitral valve disease (MMVD) ... more


Pure- and part-bred Labradors

$14 Labrador centronuclear myopathy (CNM) ... more

$14 Labrador exercise induced collapse (EIC) ... more

$14 Labrador hereditary nasal parakeratosis (HNPK) ... more


Pure- and part-bred NSDTR

$14 Cleft lip/palate and syndactyly (CLPS) ... more

$14 Cleft palate (CP1) ... more


Pure- and part-bred bulldog breeds

$26 Cystinuria (Bulldog risk markers) ... more

$14 Screw tail ... more


Working dogs

$14 Cerebellar abiotrophy marker (LINGO3) (CA LINGO3) ... more

$14 Cerebellar abiotrophy marker (VMP1) (CA VMP1)

$14 Collie eye anomaly (CEA) ... more

$14 Trapped neutrophil syndrome (TNS) ... more

Tests can be in the list more than once when the gene in question has more than one effect. It is OK to select the same test once or more than once, the price is the same.