We are taking an Easter break between the Easter and ANZAC day long weekends. You can still place orders now, and also while we are on break. If we we receive but don't finish testing your samples before Easter they will be at the top of our list when we re-open.
Cerebellar ataxia (CA1)
Summary
Dogs affected by this form of CA (CA1) show a loss of coordination with erratic leg movements, head tremor and impaired balance from around four weeks old. Their ability to balance and to sense the position of their limbs is also reduced compared to healthy dogs.
CA1 is an autosomal recessive disorder. Autosomal disorders are equally likely to affect male or female dogs, while "recessive" means that a dog needs to inherit the CA1 mutation from both its parents to be affected.
Dogs that are carriers for CA1 are not affected themselves but can potentially produce affected pups. They should not be bred to other carriers.
Gene or region and technical reference
Gene: RALGAPA1 (causative). Reference: Christen et al. (2023)
Reported alleles
n. Test developed using artificial DNA, animal controls.
CA1. Test developed using articifial DNA.
Panels: groups of tests that are often ordered together
This test is in the Belgian Shepherd health mini-panel.
