We are taking an Easter break between the Easter and ANZAC day long weekends. You can still place orders now, and also while we are on break. If we we receive but don't finish testing your samples before Easter they will be at the top of our list when we re-open.
Cardiomyopathy and juvenile mortality (CJM)
Summary
Cardiomyopathy and juvenile mortality (CJM) is an inherited disorder known to affect Belgian Shepherd breeds. Pups with CJM die suddenly at 6-9 weeks of age, most likely due to heart failure resulting from cardiomyopathy. CJM is one of the more common inherited disorders in Belgian Shepherd dog breeds.
CJM is an autosomal recessive disorder. Autosomal disorders are equally likely to affect male or female dogs, while "recessive" means that a dog needs to inherit the CJM mutation from both its parents to be affected.
Dogs that are carriers for CJM are not affected themselves but can potentially produce affected pups. They should not be bred to other carriers.
Gene or region and technical reference
Gene: YARS2 (causative). Reference: Gurtner et al. (2020)
Reported alleles
n. Test developed using artificial DNA, animal controls.
CJM. Test developed using articifial DNA.
Panels: groups of tests that are often ordered together
This test is in the Belgian Shepherd health mini-panel.
