Sorry, we aren't taking any more orders this week.

We are flat out! We want to keep doing a good job for our clients so we've taken the step of capping the number of orders we accept. If we don't do this, the turnaround time for testing will keep getting longer and longer.

Orders for each new week open on Monday, Sydney time. We are working to find ways to test more samples every day, and we will increase the weekly cap as soon as we can.

In the mean time, have a look through our individual tests and panels (panels are groups of tests) to help decide what you want to test for.

Trapped neutrophil syndrome (TNS)

Summary

Trapped neutrophil syndrome (TNS) is a disorder that impacts the immune system. Dogs with TNS can show early infections starting at around six weeks of age, react badly to immunisation, or be smaller than their litter mates. They usually struggle with frequent or ongoing infections, and most end up being euthanised.

TNS is found in all lines of border collies and may also be present in working Kelpies due to interbreeding in the past.

TNS is an autosomal recessive disorder. Autosomal disorders are equally likely to affect male or female dogs, while "recessive" means that a dog needs to inherit the TNS mutation from both its parents to be affected.

Gene or region and technical reference

Gene: VPS13B (causative). Reference: Shearman and Wilton, 2011.

Reported alleles

n. Test developed using artificial DNA and animal controls.

TNS. Test developed using artificial DNA and animal cases.

Panels: groups of tests that are often ordered together

This test is in the working dog core panel.

Order tests

There is a one-off sample processing fee of $40 per animal plus the cost of your tests.

How many animals are you testing? Discount or society code:


Pedigree

$33 A DNA profile ... more


Panels


Colour panels

$25 Brown coat colour ... more


Working dogs

$26 Working dog CA (CA panel) ... more

$54 Working dog core panel ... more


Good looks


Coat characteristics

$9 Coat length L (common form) (L) ... more

$9 Coat length L2 (L2) ... more

$9 Curly coat ... more

$9 Improper coat ... more


Good looks


Coat colour

$9 Brown (bc allele) ... more

$9 Brown (bd allele) ... more

$9 Brown (bs allele) ... more

$9 Dilution type 2 ... more


Good health


Multiple breeds

$14 Degenerative myelopathy (DM) ... more

$14 Progressive retinal atrophy - PRCD (PRA-PRCD) ... more


Working dogs

$14 Cerebellar abiotrophy marker (LINGO3) (CA: LINGO3) ... more

$14 Cerebellar abiotrophy marker (VMP1) (CA: VMP1) ... more

$14 Collie eye anomaly (CEA) ... more

$14 Trapped neutrophil syndrome (TNS)

Tests can be in the list more than once when the gene in question has more than one effect. It is OK to select the same test once or more than once, the price is the same.