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Hyperuricosuria (HUU)

Summary

Hyperuricosuria is a disorder where dogs produce high amount of uric acid in their urine. This in turn can lead to bladder and kidney stones. Owners might notice that their dogs urinate even more than other dogs (yes, really), or that they struggle to urinate, have blood in their urine, or are depressed and reluctant to move.

Hyperuricosuria is most common in Dalmation dogs but can occur in a range of dogs including but not limited to British Bulldogs, French Bulldogs and Staffordshire Terriers.

Hyperuricosuria is an autosomal recessive disorder. Autosomal disorders are equally likely to affect male or female dogs, while "recessive" means that a dog needs to inherit the HUU mutation from both its sire and its dam to be affected. Dogs that carry only one copy of this gene are not affected by this disorder, but can produce affected pups.

Gene or region and technical reference

Gene: SLC2A9 (causative). Reference: Bannasch et al. (2008)

Reported alleles

n. Test developed using artificial DNA, animal controls.

HUU. Test developed using artificial DNA, animal carriers.

Panels: groups of tests that are often ordered together

This test is not in any panels.

Order tests

There is a one-off sample processing fee of $40 per animal plus the cost of your tests.

How many animals are you testing? Discount or society code:


Panels


Colour panels

$24 B locus ... more

$16 D locus ... more

$16 E locus ... more


Working dogs

$59 Australian Kelpie panel ... more

$26 Working dog CA ... more

$54 Working dog core panel ... more


Good looks


Coat characteristics

$9 Coat length L (common form) (L) ... more

$9 Coat length L2 (L2) ... more

$9 Curly coat ... more

$9 Improper coat ... more


Good health


Australian Kelpies

$14 Intestinal lipid malabsorption (ILM) ... more


Pure- and part-bred Labradors

$14 Labrador centronuclear myopathy (CNM) ... more


Good looks


Coat colour

$9 B locus brown (bc allele) (bc) ... more

$9 B locus brown (bd allele) (bd) ... more

$9 B locus brown (bs allele) (bs) ... more

$9 D locus dilute d (common type) (d) ... more

$9 D locus dilute d2 (Chow Chow type) (d2) ... more

$9 E locus melanistic mask ... more

$9 E locus red/black ... more


Good health


Multiple breeds

$14 Airways oedema ... more

$14 Degenerative myelopathy (DM) ... more

$14 Hyperuricosuria (HUU)

$14 Myxomatous mitral valve disease (MMVD) ... more

$14 Progressive retinal atrophy - PRCD (PRA-PRCD) ... more

$14 Progressive retinal atrophy CORD1 (PRA-cord1) ... more

$14 Screw tail ... more


Working dogs

$14 Cerebellar abiotrophy marker (LINGO3) (CA: LINGO3) ... more

$14 Cerebellar abiotrophy marker (VMP1) (CA: VMP1) ... more

$14 Collie eye anomaly (CEA) ... more

$14 Trapped neutrophil syndrome (TNS) ... more

Tests can be in the list more than once when the gene in question has more than one effect. It is OK to select the same test once or more than once, the price is the same.