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Cerebellar abiotrophy marker (VMP1) (CA:VMP1)

Summary

Cerebellar abiotrophy (CA) has been reported in working Kelpies. Dogs affected by CA can show head or neck tremors, problems with their balance, exaggerated or erratic leg movement and problems eating or drinking from a bowl.

This test (CA: VMP1) is associated with a form of CA that first appears in young dogs rather than pups. Some owners noted that these dogs are physically small as well as having CA.

A positive result for this test (A A) does not guarantee that your dog will develop CA, but it is a strong guide. In the original study, 8 of 13 dogs with later-onset CA had an A A result for this marker, while none of the healthy dogs showed the same A A result.

Other possible results for this test are A C or C C. Dogs with an A C result do not have a high risk of CA but can potentially produce A A pups.

This form of CA has been found in border collies as well as Kelpies.

Gene or region and technical reference

Gene: VMP1 (marker). Reference: Pan. (2017) Thesis

Reported alleles

C. Test developed using manufactured DNA, animal controls.

A. Test developed using manufactured DNA, animal cases.

Panels: groups of tests that are often ordered together

This test is in the working dog CA panel.


dog

This form of CA has been diagnosed in dogs between 4 and 16 months old.

Order tests

There is a one-off sample processing fee of $40 per animal plus the cost of your tests.

How many animals are you testing? Discount or society code:


Pedigree

$33 A DNA profile ... more


Panels


Colour panels

$25 Brown coat colour ... more


Working dogs

$40 Working dog CA (CA panel) ... more


Good looks


Coat characteristics

$9 Coat length L (common form) (L) ... more

$9 Coat length L2 (L2) ... more

$9 Curly coat ... more

$9 Improper coat ... more


Good looks


Coat colour

$9 Brown (bc allele) ... more

$9 Brown (bd allele) ... more

$9 Brown (bs allele) ... more

$9 Dilution type 2 ... more


Good health


Multiple breeds

$14 Collie eye anomaly (CEA) ... more

$14 Degenerative myelopathy (DM) ... more

$14 Progressive retinal atrophy - PRCD (PRA-PRCD) ... more


Working dogs

$14 Cerebellar abiotrophy marker (LINGO3) (CA: LINGO3) ... more

$14 Cerebellar abiotrophy marker (NUP153) (CA: NUP153) ... more

$14 Cerebellar abiotrophy marker (VMP1) (CA:VMP1)

Tests can be in the list more than once when the gene in question has more than one effect. It is OK to select the same test once or more than once, the price is the same.