Cerebellar abiotrophy marker (VMP1) (CA: VMP1)

Summary

Cerebellar abiotrophy (CA) has been reported in working Kelpies. Dogs affected by CA can show head or neck tremors, problems with their balance, exaggerated or erratic leg movement and problems eating or drinking from a bowl.

This test (CA: VMP1) is associated with a form of CA that first appears in young dogs rather than pups.

A positive result for this test (A A) is a strong guide that your dog has or will develop CA. In the original study, 8 of 13 dogs with later-onset CA had an A A result for this marker, while none of the healthy dogs showed the same A A result.

Other possible results for this test are A C or C C. Dogs with an A C result do not have a high risk of CA but can potentially produce A A pups.

This form of CA has been found in border collies as well as Kelpies.

More info...

Gene or region and technical reference

Gene: VMP1 (marker). Reference: Pan. (2017) Thesis

Reported alleles

C. Test developed using manufactured DNA, animal controls.

A. Test developed using manufactured DNA, animal cases.

Panels: groups of tests that are often ordered together

This test is in the Australian Kelpie panel.

This test is in the working dog CA panel.

This test is in the working dog core panel.


dog

This form of CA has been diagnosed in dogs between 4 and 16 months old.

Order tests

There is a one-off sample processing fee of $40 per animal plus the cost of your tests.

How many animals are you testing? Discount or society code:


Panels


Colour panels

$25 Brown coat colour ... more


Working dogs

$59 Australian Kelpie panel ... more

$26 Working dog CA (CA panel) ... more

$54 Working dog core panel ... more


Good looks


Coat characteristics

$9 Coat length L (common form) (L) ... more

$9 Coat length L2 (L2) ... more

$9 Curly coat ... more

$9 Improper coat ... more


Good health


Australian Kelpies

$14 Intestinal lipid malabsorption (ILM) ... more


Good looks


Coat colour

$9 Brown (bc allele) ... more

$9 Brown (bd allele) ... more

$9 Brown (bs allele) ... more

$9 Dilution type 2 ... more


Good health


Multiple breeds

$14 Degenerative myelopathy (DM) ... more

$14 Progressive retinal atrophy - PRCD (PRA-PRCD) ... more


Working dogs

$14 Cerebellar abiotrophy marker (LINGO3) (CA: LINGO3) ... more

$14 Cerebellar abiotrophy marker (VMP1) (CA: VMP1)

$14 Collie eye anomaly (CEA) ... more

$14 Trapped neutrophil syndrome (TNS) ... more

Tests can be in the list more than once when the gene in question has more than one effect. It is OK to select the same test once or more than once, the price is the same.