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Progressive retinal atrophy - PRCD (PRA-PRCD)
Summary
PRA-PRCD causes late-onset blindness in dogs. Dogs with PRA-PRCD go night-blind first as the rod cells in their retina are lost. They go completely blind when the cone cells in the retina also die.
Breeds known to be affected by PRA-PRCD include Miniature and Toy poodles, Australian cattle dogs (including stumpy-tailed cattle dogs), Silky terriers, Labrador retrievers and Nova Scotia Duck Tolling Retrievers.
Cavoodles and other poodle crosses that are not first-generation crosses are also at risk of PRA-PRCD.
PRA-PRCD is an autosomal recessive disorder. Autosomal disorders are equally likely to affect male or female dogs, while "recessive" means that a dog needs to inherit the PRA-PRCD mutation from both its parents to be affected.
Gene or region and technical reference
Gene: PRCD (causative). Reference: Zangerl et al. (2006)
Reported alleles
n. Test developed using manufactured DNA, animal controls.
PRCD. Test developed using manufactured DNA, animal cases.
Panels: groups of tests that are often ordered together
This test is not in any panels.
